Article
Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
Diabetes - 1 Feb 2009
Timpson Nicholas J, Lindgren Cecilia M, Weedon Michael N, Randall Joshua, Ouwehand Willem H, Strachan David P, Rayner N William, Walker Mark, Hitman Graham A, Doney Alex S F, Palmer Colin N A, Morris Andrew D, Hattersley Andrew T, Zeggini Eleftheria, Frayling Timothy M, McCarthy Mark I
Abstract excerpt
OBJECTIVE: This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes association and considered the implications for the etiological heterogeneity of type 2 diabetes. RESEARCH DESIGN AND METHODS: We reanalyzed data from the Wellcome Trust Case Control Consortium genome-wide association scan (1,924 case subjects, 2,938 control...
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