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Article

The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies.

BMC medical genetics - 22 May 2008

Cauchi Stéphane, Nead Kevin T, Choquet Hélène, Horber Fritz, Potoczna Natascha, Balkau Beverley, Marre Michel, Charpentier Guillaume, Froguel Philippe, Meyre David

Abstract excerpt

BACKGROUND: Considering that a portion of the heterogeneity amongst previous replication studies may be due to a variable proportion of obese subjects in case-control designs, we assessed the association of genetic variants with type 2 diabetes (T2D) in large groups of obese and non-obese subjects. METHODS: We genotyped RETN, KCNJ11, HNF4A, HNF1A, GCK, SLC30A8, ENPP1, ADIPOQ, PPARG, and TCF7L2 polymorphisms in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18498634
DOI: 10.1186/1471-2350-9-45
PMCID: PMC2412856

Genes

ENPP1
ADIPOQ
GCK
PPARG
KCNJ11
RETN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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