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Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond.

Diabetologia - 1 Aug 2014

Grarup Niels, Sandholt Camilla H, Hansen Torben, Pedersen Oluf

Abstract excerpt

During the past 7 years, genome-wide association studies have shed light on the contribution of common genomic variants to the genetic architecture of type 2 diabetes, obesity and related intermediate phenotypes. The discoveries have firmly established more than 175 genomic loci associated with these phenotypes. Despite the tight correlation between type 2 diabetes and obesity, these conditions do not appear to...

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Identifiers

PMID: 24859358
DOI: 10.1007/s00125-014-3270-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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