Article
Mechanisms of disease: genetic insights into the etiology of type 2 diabetes and obesity.
Nature clinical practice. Endocrinology & metabolism - 1 Mar 2008
Lindgren Cecilia M, McCarthy Mark I
Abstract excerpt
Until recently, progress in identification of the genetic variants influencing predisposition to common forms of diabetes and obesity has been slow, a sharp contrast to the large number of genes implicated in rare monogenic forms of both conditions. Recent advances have transformed the situation, however, enabling researchers to undertake well-powered scans able to detect association signals across the entire...
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