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Article

Extrinsic control of Wnt signaling in the intestine

5 Aug 2017

Abstract excerpt

The canonical Wnt/β-catenin signaling pathway is a central regulator of development and tissue homeostasis. In the intestine, Wnt signaling is primarily known as the principal organizer of epithelial stem cell identity and proliferation. Within the last decade, numerous scientific breakthroughs have shed light on epithelial self-organization in the gut, and organoids are now routinely used to study stem cell...

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PMID: 28802143
DOI: 10.1016/j.diff.2017.08.003

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