Article
Association between common mtDNA variants and all-cause or colorectal cancer mortality.
Carcinogenesis - 1 Feb 2010
Theodoratou Evropi, Din Farhat V N, Farrington Susan M, Cetnarskyj Roseanne, Barnetson Rebecca A, Porteous Mary E, Dunlop Malcolm G, Campbell Harry, Tenesa Albert
Abstract excerpt
Mutations in the mitochondrial DNA (mtDNA) have been found to be present in several types of tumours including tumours of the large bowel. However, their role in cancer development and prognosis is still to be resolved. We used 2838 cases from a large Scottish colorectal cancer (CRC) case-control...
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