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Article

Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiation

28 Nov 2008

Abstract excerpt

The Wilms' tumour suppressor protein WT1 plays a central role in the development of the kidney and also other organs. WT1 can act as a transcription factor with highly context-specific activator and repressor functions. We previously identified Brain Acid Soluble Protein 1 (BASP1) as a transcriptional cosuppressor that can block the transcriptional activation function of WT1. WT1 and BASP1 are co-expressed during...

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Identifiers

PMID: 19050011
DOI: 10.1093/nar/gkn955

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Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiationPMID 19050011Read ↗

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