WT1--more than a transcription factor?

doi:10.1016/s0968-0004(98)01277-8

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Article

WT1--more than a transcription factor?

Trends in biochemical sciences - 1 Oct 1998

Englert C

Abstract excerpt

The Wilms tumor-suppressor gene WT1 was originally identified through its involvement in the development of a pediatric kidney tumor. Recent genetic data show that mutations in the WT1 gene cause a variety of other diseases, and new biochemical evidence suggests that the WT1 protein is not only a...

Topics

Alternative Splicing
Animals
DNA-Binding Proteins
Genes, Wilms Tumor
Humans
Kidney
Mice
Mice, Knockout
Mutation
Transcription Factors
WT1 Proteins

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