Article
BASP1 Is a Transcriptional Cosuppressor for the Wilms' Tumor Suppressor Protein WT1
31 Dec 2003
Abstract excerpt
The Wilms' tumor suppressor protein WT1 is a transcriptional regulator that plays a key role in the development of the kidneys. The transcriptional activation domain of WT1 is subject to regulation by a suppression region within the N terminus of WT1. Using a functional assay, we provide direct evidence that this requires a transcriptional cosuppressor, which we identify as brain acid soluble protein 1 (BASP1)....
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