Identification of WTAP, a novel Wilms' tumour 1-associating protein

doi:10.1093/oxfordjournals.hmg.a018914

Article

Identification of WTAP, a novel Wilms' tumour 1-associating protein

1 Sept 2000

Abstract excerpt

The Wilms' tumour suppressor gene WT1 is essential for the normal development of the genitourinary system. It appears to play a role in both transcriptional and post-transcriptional regulation of certain cellular genes. However, the mechanisms behind WT1 function are not clearly understood despite the identification of numerous potential target genes and the isolation of several WT1-binding proteins. This study...

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