Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus.

The Journal of biological chemistry - 2 Apr 2004

Srichai Manakan B, Konieczkowski Martha, Padiyar Aparna, Konieczkowski David J, Mukherjee Amitava, Hayden Patrick S, Kamat Sweta, El-Meanawy M Ashraf, Khan Shenaz, Mundel Peter, Lee Sean Bong, Bruggeman Leslie A, Schelling Jeffrey R, Sedor John R

Abstract excerpt

Glomerular podocyte differentiation state is critical for filtration barrier function and is regulated by WT1, a zinc finger transcription factor. A yeast two-hybrid assay identified a novel, WT1-interacting protein (WTIP) that maps to human chromosome 19q13.1, a region with genes linked to famil...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adherens Junctions
Share to Cell Aggregation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Co-Repressor Proteins

Share to COS Cells

Share to Kidney Glomerulus

Share to NIH 3T3 Cells

Share to Two-Hybrid System Techniques

Share to WT1 Proteins

Source

Identifiers

PMID: 14736876
DOI: 10.1074/jbc.M314155200

Genes

WTIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14736876-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus.PMID 14736876Read ↗

Out on a LIM: chronic kidney disease, podocyte phenotype and the Wilm's tumor interacting protein (WTIP).Semantic proximity Read ↗

WT1-interacting protein (Wtip) regulates podocyte phenotype by cell-cell and cell-matrix contact reorganization.Semantic proximity Read ↗

Towards an understanding of kidney diseases associated with WT1 mutations.Semantic proximity Read ↗

Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.Semantic proximity Read ↗

Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injurySemantic proximity Read ↗

Motor Protein Myo1c Is a Podocyte Protein That Facilitates the Transport of Slit Diaphragm Protein Neph1 to the Podocyte MembraneSemantic proximity Read ↗

Altering a histone H3K4 methylation pathway in glomerular podocytes promotes a chronic disease phenotype.Semantic proximity Read ↗

Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injurySemantic proximity Read ↗

A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development.Semantic proximity Read ↗

Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms’ Tumor 1 Target Genes in Podocyte Differentiation and MaintenanceSemantic proximity Read ↗

Dnmbp interacts with Daam1 to facilitate assembly of cadherin-mediated junctions in epithelializing nephric tubulesSemantic proximity Read ↗

Transcriptional regulation of podocyte specification and differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.