Article
Identification of Fat4 as a candidate tumor suppressor gene in breast cancers.
International journal of cancer - 15 Feb 2009
Qi Chao, Zhu Yiwei Tony, Hu Liping, Zhu Yi-Jun
Abstract excerpt
Fat, a candidate tumor suppressor in Drosophila, is a component of Hippo signaling pathway involved in controlling organ size. We found that a approximately 3 Mbp deletion in mouse chromosome 3 caused tumorigenesis of a non-tumorigenic mammary epithelial cell line. The expression of Fat4 gene, on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
