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Article

Hepatitis B virus genotypes and resistance mutations in patients under long term lamivudine therapy: characterization of genotype G in Brazil.

BMC microbiology - 22 Jan 2008

Bottecchia Marcelle, Souto Francisco J D, O Kycia M R, Amendola Marcia, Brandão Carlos E, Niel Christian, Gomes Selma A

Abstract excerpt

BACKGROUND: Lamivudine is an oral nucleoside analogue widely used for the treatment of chronic hepatitis B. The main limitation of lamivudine use is the selection of resistant mutations that increases with time of utilization. Hepatitis B virus (HBV) isolates have been classified into eight genotypes (A to H) with distinct geographical distributions. HBV genotypes may also influence pathogenic properties and...

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Identifiers

PMID: 18211717
DOI: 10.1186/1471-2180-8-11
PMCID: PMC2245951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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