Article
High frequency of lamivudine resistance mutations in Brazilian patients co-infected with HIV and hepatitis B.
Journal of medical virology - 1 Sept 2010
Mendes-Correa M C, Pinho J R R, Locarnini S, Yuen L, Sitnik R, Santana R A F, Gomes-Gouvêa M S, Leite O M, Martins L G, Silva M H, Gianini R J, Uip D E
Abstract excerpt
This study analyzed the genotype distribution and frequency of lamivudine (LAM) and tenofovir (TDF) resistance mutations in a group of patients co-infected with HIV and hepatitis B virus (HBV). A cross-sectional study of 847 patients with HIV was conducted. Patients provided blood samples for HBsAg detection. The load of HBV was determined using an "in-house" real-time polymerase chain reaction. HBV...
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