Article
rasiRNA pathway controls antisense expression of Drosophila telomeric retrotransposons in the nucleus.
Nucleic acids research - 1 Jan 2009
Shpiz Sergey, Kwon Dmitry, Rozovsky Yakov, Kalmykova Alla
Abstract excerpt
Telomeres in Drosophila are maintained by the specialized telomeric retrotransposons HeT-A, TART and TAHRE. Sense transcripts of telomeric retroelements were shown to be the targets of a specialized RNA-interference mechanism, a repeat-associated short interfering (rasi)RNA-mediated system. Antisense rasiRNAs play a key role in this mechanism, highlighting the importance of antisense expression in retrotransposon...
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