Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trim24 (Tif1 alpha): an essential 'brake' for retinoic acid-induced transcription to prevent liver cancer.

Cell cycle (Georgetown, Tex.) - 1 Dec 2008

Khetchoumian Konstantin, Teletin Marius, Tisserand Johan, Herquel Benjamin, Ouararhni Khalid, Losson Régine

Abstract excerpt

Retinoic acid (RA), the active derivative of vitamin A, is an important signaling molecule that controls various developmental processes and influence the proliferation and differentiation of a variety of cell types. RA exerts its biological functions primarily through binding to and activating nuclear RA receptors (RARs, which include the RAR alpha, beta and gamma isotypes RARA, RARB and RARC). Aberrant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Hepatocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeostasis

Share to Liver Neoplasms

Share to Polyploidy

Share to Receptors, Retinoic Acid

Share to Retinoic Acid Receptor alpha

Share to Tretinoin

Source

Identifiers

PMID: 19029830
DOI: 10.4161/cc.7.23.7123

Genes

RARA
RARB
TRIM24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trim24 (Tif1 alpha): an essential 'brake' for retinoic acid-induced transcription to prevent liver cancer.PMID 19029830Read ↗

Tripartite Motif 24 (Trim24/Tif1α) Tumor Suppressor Protein Is a Novel Negative Regulator of Interferon (IFN)/Signal Transducers and Activators of Transcription (STAT) Signaling Pathway Acting through Retinoic Acid Receptor α (Rarα) InhibitionSemantic proximity Read ↗

Overexpression of TRIM24 Is Associated with the Onset and Progress of Human Hepatocellular CarcinomaSemantic proximity Read ↗

Tripartite motif-containing protein 21 is involved in IFN-γ-induced suppression of hepatitis B virus by regulating hepatocyte nuclear factorsSemantic proximity Read ↗

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.Semantic proximity Read ↗

Orphan nuclear receptors recruit TRIM28 to promote telomeric H3K9me3 for the alternative lengthening of telomeres pathwaySemantic proximity Read ↗

The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome.Semantic proximity Read ↗

TRIM32 promotes neural differentiation through retinoic acid receptor-mediated transcription.Semantic proximity Read ↗

The orphan nuclear receptor TR4 is a vitamin A-activated nuclear receptor.Semantic proximity Read ↗

Role of the Tripartite Motif Protein 27 in Cancer DevelopmentSemantic proximity Read ↗

Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid–Activated ReceptorSemantic proximity Read ↗

SUMOylation negatively regulates transcriptional and oncogenic activities of MafA.Semantic proximity Read ↗

The ubiquitin ligase TRIM25 inhibits hepatocellular carcinoma progression by targeting metastasis associated 1 proteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.