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Article

Asthma and atopy are associated with chromosome 17q21 markers in Chinese children.

Allergy - 1 Apr 2009

Leung T F, Sy H Y, Ng M C Y, Chan I H S, Wong G W K, Tang N L S, Waye M M Y, Lam C W K

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphism (SNP)-based genome-wide association study revealed that markers on chromosome 17q21 were linked to childhood asthma but not atopy in Caucasians, with the strongest signal being detected for the SNP rs7216389 in the ORMDL3 gene. Such association was unknown in Chinese. This study delineated the allele and genotype frequencies of 10 SNPs at chromosome 17q21, and...

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Source

Identifiers

PMID: 19175592
DOI: 10.1111/j.1398-9995.2008.01873.x

Genes

ORMDL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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