Article
17q12-21 and asthma: interactions with early-life environmental exposures.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 May 2013
Blekic Mario, Kljaic Bukvic Blazenka, Aberle Neda, Marinho Susana, Hankinson Jenny, Custovic Adnan, Simpson Angela
Abstract excerpt
BACKGROUND: 17q12-21 polymorphisms are associated with asthma presence and severity across different populations. OBJECTIVE: To extensively investigate the genes in this region among Croatian schoolchildren in a case-control study, taking account of early-life environmental exposures. METHODS: We included 423 children with asthma and 414 controls aged 5 to 18 years. Fifty-one haplotype tagging single-nucleotide...
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