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Article

Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.

The New England journal of medicine - 11 Apr 2013

Calışkan Minal, Bochkov Yury A, Kreiner-Møller Eskil, Bønnelykke Klaus, Stein Michelle M, Du Gaixin, Bisgaard Hans, Jackson Daniel J, Gern James E, Lemanske Robert F, Nicolae Dan L, Ober Carole

Abstract excerpt

BACKGROUND: Both genetic variation at the 17q21 locus and virus-induced respiratory wheezing illnesses are associated with the development of asthma. Our aim was to determine the effects of these two factors on the risk of asthma in the Childhood Origins of Asthma (COAST) and the Copenhagen Prospective Study on Asthma in Childhood (COPSAC) birth cohorts. METHODS: We tested genotypes at the 17q21 locus for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23534543
DOI: 10.1056/NEJMoa1211592
PMCID: PMC3755952

Genes

GSDMB
ORMDL3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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