Article
Human B Lymphomas Reveal Their Secrets Through Genetic Mouse Models.
Frontiers in immunology - 1 Jan 2021
Mossadegh-Keller Noushin, Brisou Gabriel, Beyou Alicia, Nadel Bertrand, Roulland Sandrine
Abstract excerpt
Lymphomas are cancers deriving from lymphocytes, arising preferentially in secondary lymphoid organs, and represent the 6th cancer worldwide and the most frequent blood cancer. The majority of B cell Non-Hodgkin lymphomas (B-NHL) develop from germinal center (GC) experienced mature B cells. GCs are transient structures that form in lymphoid organs in response to antigen exposure of naive B cells, and where B cell...
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