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Article

Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta.

The Journal of experimental medicine - 1 May 1991

Pullen A M, Bill J, Kubo R T, Marrack P, Kappler J W

Abstract excerpt

Superantigen bound to major histocompatibility complex (MHC) products have been shown to stimulate T cells in a V beta-specific manner. Mouse T cells bearing V beta 8.1 usually respond to the self superantigen, Mls-1a, whereas T cells bearing V beta 8.2a do not. Previously, using site-directed mutational analysis, we identified the residues of natural variants of T cell receptor (TCR) V beta 8.2 that conferred...

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Identifiers

PMID: 1902503
DOI: 10.1084/jem.173.5.1183
PMCID: PMC2118855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta.PMID 1902503Read ↗

Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a.Semantic proximity Read ↗

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Recognition of a single amino acid change on the surface of a major transplantation antigen is in the context of self peptide.Semantic proximity Read ↗

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