Article
Mouse mammary tumor virus superantigens require N-linked glycosylation for effective presentation to T cells.
Virology - 17 Feb 1997
McMahon C W, Bogatzki L Y, Pullen A M
Abstract excerpt
Mouse mammary tumor viruses (MMTVs) encode superantigens that associate with major histocompatibility complex class II products on antigen-presenting cells and stimulate T cells in a V beta-specific manner. This T cell activation is critical for completion of the viral life cycle and vertical transmission to the next generation. To investigate the functional significance of extensive viral superantigen (Sag)...
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