Article
Presentation of the Mls-1 superantigen by human HLA class II molecules to murine T cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1993
Subramanyam M, McLellan B, Labrecque N, Sekaly R P, Huber B T
Abstract excerpt
Superantigens (SAG) presented in the context of MHC class II proteins stimulate a strong proliferative response in T cells expressing particular TCR V beta genes. Although this T-cell recognition is not MHC restricted, a strong hierarchy is observed in the ability of various MHC class II molecules to present SAG. Mls-1, encoded by the Murine Mammary Tumor Virus (MMTV) Mtv-7 sag gene, is the prototype of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
