Presentation of the Mls-1 superantigen by human HLA class II molecules to murine T cells.

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Article

Presentation of the Mls-1 superantigen by human HLA class II molecules to murine T cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1993

Subramanyam M, McLellan B, Labrecque N, Sekaly R P, Huber B T

Abstract excerpt

Superantigens (SAG) presented in the context of MHC class II proteins stimulate a strong proliferative response in T cells expressing particular TCR V beta genes. Although this T-cell recognition is not MHC restricted, a strong hierarchy is observed in the ability of various MHC class II molecule...

Topics

Alleles
Animals
Antibodies, Monoclonal
HLA-DR Antigens
Histocompatibility Antigens Class II
Lymphocyte Activation
Mammary Tumor Virus, Mouse
Mice
Mice, Inbred CBA
Minor Lymphocyte Stimulatory Antigens
Receptors, Antigen, T-Cell, alpha-beta
T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 8395548

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8395548-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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