Article
A fungus-specific ras homolog contributes to the hyphal growth and virulence of Aspergillus fumigatus.
Eukaryotic cell - 1 Dec 2005
Fortwendel Jarrod R, Zhao Wei, Bhabhra Ruchi, Park Steven, Perlin David S, Askew David S, Rhodes Judith C
Abstract excerpt
The Ras family of GTPase proteins has been shown to control morphogenesis in many organisms, including several species of pathogenic fungi. In a previous study, we identified a gene encoding a fungus-specific Ras subfamily homolog, rasB, in Aspergillus fumigatus. Here we report that deletion of A. fumigatus rasB caused decreased germination and growth rates on solid media but had no effect on total biomass...
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