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Article

Synapsis and catalysis by activated Tn3 resolvase mutants.

Nucleic acids research - 1 Dec 2008

Olorunniji Femi J, He Jiuya, Wenwieser Sandra V C T, Boocock Martin R, Stark W Marshall

Abstract excerpt

The serine recombinase Tn3 resolvase catalyses recombination between two 114 bp res sites, each of which contains binding sites for three resolvase dimers. We have analysed the in vitro properties of resolvase variants with 'activating' mutations, which can catalyse recombination at binding site I of res when the rest of res is absent. Site I x site I recombination promoted by these variants can be as fast as res...

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Identifiers

PMID: 19015124
DOI: 10.1093/nar/gkn885
PMCID: PMC2602789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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