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Article

Structure of a synaptic gammadelta resolvase tetramer covalently linked to two cleaved DNAs.

Science (New York, N.Y.) - 19 Aug 2005

Li Weikai, Kamtekar Satwik, Xiong Yong, Sarkis Gary J, Grindley Nigel D F, Steitz Thomas A

Abstract excerpt

The structure of a synaptic intermediate of the site-specific recombinase gammadelta resolvase covalently linked through Ser10 to two cleaved duplex DNAs has been determined at 3.4 angstrom resolution. This resolvase, activated for recombination by mutations, forms a tetramer whose structure is substantially changed from that of a presynaptic complex between dimeric resolvase and the cleavage site DNA. Because...

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Source

Identifiers

PMID: 15994378
DOI: 10.1126/science.1112064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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