Article
The two functional domains of gamma delta resolvase act on the same recombination site: implications for the mechanism of strand exchange.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990
Dröge P, Hatfull G F, Grindley N D, Cozzarelli N R
Abstract excerpt
During site-specific recombination by the gamma delta resolvase, four DNA strands are broken, exchanged, and religated. This exchange is carried out within a DNA-protein complex, the synaptosome, in which the recombination sites, res, are aligned. The domain of resolvase that binds to a res site is distinct from the domain that breaks and rejoins the DNA. We tested whether the catalytic domain acts on the res...
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