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Article

Gene set enrichment analysis for non-monotone association and multiple experimental categories.

BMC bioinformatics - 14 Nov 2008

Lin Rongheng, Dai Shuangshuang, Irwin Richard D, Heinloth Alexandra N, Boorman Gary A, Li Leping

Abstract excerpt

BACKGROUND: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression (SAFE), have gained recognition as a way to identify biological pathways/processes associated with a phenotypic endpoint. In these analyses, a local statistic is used to assess the association between the expression level of a gene and...

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Identifiers

PMID: 19014579
DOI: 10.1186/1471-2105-9-481
PMCID: PMC2636811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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