Article

Molecular annotation of AOPs guides the development of the next generation mechanistic chemical safety assessment and new approach methods

2022-07-10

Abstract excerpt

Mechanistic toxicology has emerged as a powerful framework to inform on the safety of chemicals and guide the development of new safe-by-design compounds. Although toxicogenomics provides support towards mechanistic evaluation of chemical exposures, the implementation of toxicogenomics-based evidence in the regulatory setting is still hindered by uncertainties related to the analysis and interpretation of such dat...

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Literature Corpus work: 56f82f58-b407-5eaf-8102-eadf0cef2814
DOI: 10.1101/2022.07.08.499301

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