Article
A toxicity pathway-oriented approach to develop adverse outcome pathway: AHR activation as a case study.
Environmental pollution (Barking, Essex : 1987) - 1 Jan 2021
Jin Yuan, Feng Meiyao, Ma Wanli, Wei Yanhong, Qi Guangshuai, Luo Jiao, Xu Lin, Li Xinmei, Li Chuanhai, Wang Ying, Li Daochuan, Chen Jing, Zhao Yanjie, Hou Yufei, Zhao Qianwen, Jiang Lidan, Xie Mengyue, Zheng Yuxin, Yu Dianke
Abstract excerpt
With numerous new chemicals introduced into the environment everyday, identification of their potential hazards to the environment and human health is a considerable challenge. Developing adverse outcome pathway (AOP) framework is promising in helping to achieve this goal as it can bring In Vitro testing into toxicity measurement and understanding. To explore the toxic mechanism underlying environmental chemicals...
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