Article
Gene set enrichment; a problem of pathways.
Briefings in functional genomics - 1 Dec 2010
Davies Matthew N, Meaburn Emma L, Schalkwyk Leonard C
Abstract excerpt
Gene Set Enrichment (GSE) is a computational technique which determines whether a priori defined set of genes show statistically significant differential expression between two phenotypes. Currently, the gene sets used for GSE are derived from annotation or pathway databases, which often contain computationally based and unrepresentative data. Here, we propose a novel approach for the generation of comprehensive...
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