Protein material costs: single atoms can make an evolutionary difference.

Abstract excerpt

The process of gene expression has material costs caused by the quantities of carbon, nitrogen, sulfur and phosphorus that are needed to make mRNAs and proteins. When any such chemical element is ecologically limiting, mutations increasing these costs can reduce growth. Here, we ask if such mutations are 'visible' to natural selection in the yeast Saccharomyces cerevisiae. We find that mutations causing small...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amino Acid Substitution
• Share to Evolution, Molecular
• Share to Gene Expression