Article
The fitness challenge of studying molecular adaptation.
Biochemical Society transactions - 31 Oct 2019
Coombes David, Moir James W B, Poole Anthony M, Cooper Tim F, Dobson Renwick C J
Abstract excerpt
Advances in bioinformatics and high-throughput genetic analysis increasingly allow us to predict the genetic basis of adaptive traits. These predictions can be tested and confirmed, but the molecular-level changes - i.e. the molecular adaptation - that link genetic differences to organism fitness remain generally unknown. In recent years, a series of studies have started to unpick the mechanisms of adaptation at...
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