Article
Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster.
Molecular and cellular biology - 1 Apr 1991
Holdridge C, Dorsett D
Abstract excerpt
The suppressor of hairy-wing [su(Hw)] locus of Drosophila melanogaster encodes a zinc finger protein that binds a repeated motif in the gypsy retroposon. Mutations of su(Hw) suppress the phenotypes associated with mutations caused by gypsy insertions. To examine the mechanisms by which su(Hw) alters gene expression, a fragment of gypsy containing multiple su(Hw) protein-binding sites was inserted into various...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Binding Sites
- Blotting, Northern
- Cell Line
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation
- Genes