Article
Genomic organization of gypsy chromatin insulators in Drosophila melanogaster.
Genetics - 1 Apr 2006
Ramos Edward, Ghosh Dolanchanpa, Baxter Ellen, Corces Victor G
Abstract excerpt
Chromatin insulators have been implicated in the regulation of higher-order chromatin structure and may function to compartmentalize the eukaryotic genome into independent domains of gene expression. To test this possibility, we used biochemical and computational approaches to identify gypsy-like genomic-binding sites for the Suppressor of Hairy-wing [Su(Hw)] protein, a component of the gypsy insulator. EMSA and...
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