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Article

Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.

PLoS genetics - 1 Nov 2008

Li Hongchuan, Pascal Véronique, Martin Maureen P, Carrington Mary, Anderson Stephen K

Abstract excerpt

Natural killer (NK) cells play an important role in the detection and elimination of tumors and virus-infected cells by the innate immune system. Human NK cells use cell surface receptors (KIR) for class I MHC to sense alterations of class I on potential target cells. Individual NK cells only exp...

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Identifiers

PMID: 19008943
DOI: 10.1371/journal.pgen.1000254
PMCID: PMC2575236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19008943-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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