Article
Characterization of a weakly expressed KIR2DL1 variant reveals a novel upstream promoter that controls KIR expression.
Genes and immunity - 1 Oct 2014
Wright P W, Li H, Huehn A, O'Connor G M, Cooley S, Miller J S, Anderson S K
Abstract excerpt
Members of the human KIR (killer cell immunoglobulin-like receptor) class I major histocompatibility complex receptor gene family contain multiple promoters that determine the variegated expression of KIR on natural killer cells. In order to identify novel genetic alterations associated with decreased KIR expression, a group of donors was characterized for KIR gene content, transcripts and protein expression. An...
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