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Article

Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2002

Shilling Heather G, Guethlein Lisbeth A, Cheng Nathalie W, Gardiner Clair M, Rodriguez Roberto, Tyan Dolly, Parham Peter

Abstract excerpt

Killer Ig-like receptor (KIR) genes are a multigene family on human chromosome 19. KIR genes occur in various combinations on different haplotypes. Additionally, KIR genes are polymorphic. To examine how allelic polymorphism diversifies KIR haplotypes with similar or identical combinations of KIR genes, we devised methods for discriminating alleles of KIR2DL1, -2DL3, -3DL1, and -3DL2. These methods were applied...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Receptors, Immunologic

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Source

Identifiers

PMID: 11859120
DOI: 10.4049/jimmunol.168.5.2307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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