Article
Associations between common variants in the MDR1 (ABCB1) gene and ulcerative colitis among North Indians.
Pharmacogenetics and genomics - 1 Jan 2009
Juyal Garima, Midha Vandana, Amre Devendra, Sood Ajit, Seidman Ernest, Thelma B K
Abstract excerpt
OBJECTIVES: There are suggestions that the MDR1 (ABCB1) gene is associated with ulcerative colitis (UC) in Caucasians. We investigated whether common MDR1 variants were associated with UC in the genetically heterogeneous North Indian population. METHODS: Confirmed cases of UC and healthy controls frequency matched for age (+/-10 years) and geographic region were studied. Three exonic (C1236T, G2677T/A, and...
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