Article
Galectin-4-mediated transcytosis of transferrin receptor.
Journal of cell science - 15 Oct 2014
Perez Bay Andres E, Schreiner Ryan, Benedicto Ignacio, Rodriguez-Boulan Enrique J
Abstract excerpt
Some native epithelia, for example, retinal pigment epithelium (RPE) and kidney proximal tubule (KPT), constitutively lack the basolateral sorting adaptor AP-1B; this results in many basolateral plasma membrane proteins being repositioned to the apical domain, where they perform essential functions for their host organs. We recently reported the underlying apical polarity reversal mechanism: in the absence of...
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