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Article

Polarized transport of Alzheimer amyloid precursor protein is mediated by adaptor protein complex AP1-1B.

Traffic (Copenhagen, Denmark) - 1 Mar 2007

Icking Ann, Amaddii Monia, Ruonala Mika, Höning Stefan, Tikkanen Ritva

Abstract excerpt

Alzheimer amyloid precursor protein (APP) is the precursor for the Abeta peptide involved in pathogenesis of Alzheimer's disease. The soluble ectodomain fragment of APP (sAPP) functions as a growth factor for epithelial cells, suggesting an important function for APP outside neuronal tissue. Prev...

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Source

Identifiers

PMID: 17319802
DOI: 10.1111/j.1600-0854.2006.00526.x

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17319802-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Polarized transport of Alzheimer amyloid precursor protein is mediated by adaptor protein complex AP1-1B.PMID 17319802Read ↗

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