Article
Impact of cytokine gene polymorphisms on graft-vs-host disease.
Tissue antigens - 1 Dec 2008
Markey K A, MacDonald K P A, Hill G R
Abstract excerpt
Allogeneic hematopoietic stem cell transplantation (SCT) remains the only available curative therapy for hematological malignancy. It does, however, result in significant morbidity and mortality, predominantly as a consequence of infections, leukemic relapse and graft-vs-host disease (GVHD). While differences in human leukocyte antigen (HLA) molecules between donor and host make a crucial contribution to the...
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