Article
Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants.
Blood - 15 Nov 1998
Middleton P G, Taylor P R, Jackson G, Proctor S J, Dickinson A M
Abstract excerpt
It is now well known that the initial phase of graft-versus-host disease (GVHD) involves cytokine release during preconditioning of the recipient of an allogeneic bone marrow transplant (BMT). Tumor necrosis factor (TNF), in particular, has been implicated in pathological damage and is released p...
Topics
- Acute Disease
- Adolescent
- Adult
- Alleles
- Bone Marrow Transplantation
- Cause of Death
- Dinucleotide Repeats
- Female
- Graft vs Host Disease
- Granulomatous Disease, Chronic
- Hematologic Neoplasms
- Histocompatibility
- Humans
- Interleukin-10
- Male
- Middle Aged
- Myelodysplastic Syndromes
- Nuclear Family