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Article

The impact of cytokine gene polymorphisms on the outcome of HLA matched sibling hematopoietic stem cell transplantation.

Cytokine - 1 Oct 2018

Kamel Azza M, Gameel Abdallah, Ebid Gamal T A, Radwan Eman R, Mohammed Saleh Mostafa F, Abdelfattah Raafat

Abstract excerpt

Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic stem cell transplantation (HSCT); cytokines are recognized as important mediators in its pathogenesis. In this study we investigated the role of cytokine gene polymorphisms on HSCT outcome. A total of 106 patient and 98 donors were genotyped by polymerase chain reaction sequence specific primers (PCR-SSP) based assay for tumor...

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Identifiers

PMID: 29801972
DOI: 10.1016/j.cyto.2018.05.003

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