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Cytokine gene polymorphisms and graft-versus-host disease in children after matched sibling hematopoietic stem cell transplantation: a single-center experience.

Cellular & molecular immunology - 1 May 2011

Goussetis Evgenios, Varela Ioanna, Peristeri Ioulia, Kitra Vasiliki, Spanou Kleopatra, Moraloglou Olga, Paisiou Anna, Karatasaki Sofia, Soldatou Alexandra, Constantinidou Nikki, Graphakos Stelios

Abstract excerpt

Various polymorphisms in cytokine genes have recently been investigated as candidate risk factors in allogeneic hematopoetic stem cell transplantation (allo-HSCT). We retrospectively analyzed specific polymorphisms in genes for interleukin (IL)-10, IL-6, tumor-necrosis factor alpha (TNF-α) and interferon gamma (IFN-γ) in a pediatric cohort of 57 histocompatibility leucocyte antigen (HLA)-identical sibling...

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Identifiers

PMID: 21358669
DOI: 10.1038/cmi.2011.4
PMCID: PMC4012873

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