Article
The effects of gene polymorphisms on susceptibility to acute GVHD and survival of allogeneic HSCT recipients: IL-10 gene polymorphisms as a more accessible target to predict prognosis.
Human immunology - 1 Jan 2020
Granero Farias Mariela, Andrade Dos Santos Camila, de Mello Vicente Bruna, Habigzang Muriel, de Oliveira da Silva Priscila, Emerim Lemos Natália, Dieter Cristine, Paz Alessandra, Esteves Daudt Liane
Abstract excerpt
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a therapeutic modality commonly used to treat hematological and immunological disorders. Among the main complications of allo-HSCT is the acute graft-versus-host disease (a-GVHD), a condition which accounts for a high incidence of mortality. Several genes encoding inflammatory mediators may present polymorphisms, which have been implicated in the...
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