Article
Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival.
Developmental biology - 15 Feb 2009
Pontoriero Giuseppe F, Smith April N, Miller Leigh-Anne D, Radice Glenn L, West-Mays Judith A, Lang Richard A
Abstract excerpt
The classical cadherins are known to have both adhesive and signaling functions. It has also been proposed that localized regulation of cadherin activity may be important in cell assortment during development. In the context of eye development, it has been suggested that cadherins are important for separation of the invaginated lens vesicle from the surface ectoderm. To test this hypothesis, we conditionally...
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