Article
Distinct and redundant functions of Esama and VE-cadherin during vascular morphogenesis.
Development (Cambridge, England) - 15 Apr 2017
Sauteur Loïc, Affolter Markus, Belting Heinz-Georg
Abstract excerpt
The cardiovascular system forms during early embryogenesis and adapts to embryonic growth by sprouting angiogenesis and vascular remodeling. These processes require fine-tuning of cell-cell adhesion to maintain and re-establish endothelial contacts, while allowing cell motility. We have compared the contribution of two endothelial cell-specific adhesion proteins, VE-cadherin (VE-cad/Cdh5) and Esama (endothelial...
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