Article
Cell-junctional and cytoskeletal organization in mouse blastocysts lacking E-cadherin.
Developmental biology - 15 May 1997
Ohsugi M, Larue L, Schwarz H, Kemler R
Abstract excerpt
Trophectoderm epithelium formation, the first visible differentiation process during mouse embryonic development, is affected in embryos lacking the cell adhesion molecule E-cadherin. Here we analyze the developmental potential of such E-cadherin-negative embryos, focusing on the organization of cell junctions and the cytoskeleton. To do this we used antibodies directed against alpha-, beta-, or...
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