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Article

Hepatocyte growth factor inhibits epithelial to myofibroblast transition in lung cells via Smad7.

American journal of respiratory cell and molecular biology - 1 Jun 2009

Shukla Manasi N, Rose Jane L, Ray Rabindranath, Lathrop Kira L, Ray Anuradha, Ray Prabir

Abstract excerpt

Idiopathic pulmonary fibrosis is a lethal parenchymal lung disease characterized by denudation of the lung epithelium, fibroblast proliferation, and collagen deposition. Cellular changes underlying disease progression involve injury to alveolar epithelial cells, epithelial to mesenchymal transition, proliferation of alpha-smooth muscle actin (alpha-SMA)-expressing myofibroblasts and of fibroblasts resulting in...

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Source

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Identifiers

PMID: 18988920
DOI: 10.1165/rcmb.2008-0217OC
PMCID: PMC2689916

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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